When these hormones misfire, your body adjusts by changing their levels, a fluctuation that ultimately slows down the metabolism, causing you to store fat every time you eat instead of using it as fuel to energize you. When your metabolism is broken, you get fatter no matter what you do—especially after age forty—and can eventually develop insulin resistance, diabetes, heart disease, and even dementia.
I gain weight way too easily (diabetes runs in my family as does poor stress resilience), so I’m strategic with my food plan. I eat foods that stabilize my blood sugar and don’t cause high cortisol if you’re intolerant like me – that includes amping up fiber and avoiding gluten. I choose foods and drinks that are high in nutrient density, with broad diversity of species so that my microbiome is happy. I have hypothyroidism, or a slow thyroid, so I try my best to avoid raw goitrogens like cruciferous vegetables and soy. I still eat broccoli, kale, collards, cauliflower, etc. but I lightly steam them to inactivate most of the goitrogens. I like tempeh, a fermented form of whole soy, but chose the types that are not combined with grains. You’ll find a lot of fermented vegetables on my meal plan because they are nature’s probiotic and help you reset your insulin so that you don’t store fat at your belly and raise your blood sugar unnecessarily. I eat low-mercury, wild-caught fish almost daily because it keeps my fatty acids in balance. I have a gene called PPARG that keeps my weight down if I eat more fish than meat, so you’ll find a lot of salmon, halibut, cod, and steelhead trout on the menu.
I have read this book twice now and have it all highlighted and marked up. When I'm starting to feel bad and unhealthy, this is the go to book to get back on track with my health and feeling good again. The recipes in this book are easy and actually pretty good. You will learn so much about how all the different hormones work together in your body.
Oh lordy where to start. This book can be summed up into : Meditate, eat well, test hormones and try to boost what you are low in first naturally and if that is not possible, opt for bioidentical ones-strechted over 400 pages of blaaa. Peppered with tales of her grandmother mud who was an inspiration to here because she drank lemon water and looked fierce without realizing her grannie sounds like just another over-privileged California health-nut.
I like to look at the studies, see who paid for them and try to choose a middle ground. And as a side note, Dr. Greger takes proceeds from book sales for his nonprofit organization. His nonprofit employs a team of researchers to constantly stay up on all the food-related studies out there. He also does not speak with a lot of bias about particular diets being what works, as the paleo is stated more than once in Dr. Gottfried's book.
Dr. Norman's biomedical research career has focused on the mechanism of action of the vitamin D family of steroids. His chief contributions to these areas of cellular and molecular endocrinology have played a pivotal role in defining the boundaries of this research domain via discoveries that have opened new areas of investigation. The first of these was the discovery in 1968, and chemical characterization in 1971, of the hormonally active form of vitamin D, 1a,25(OH)2-vitamin D3. Subsequent achievements include the discovery and characterization of the nuclear receptor for 1a,25(OH)2D3, the clinical evaluation of 1a,25(OH)2D3 in renal osteodystrophy, articulation of the concept of the vitamin D endocrine system, the importance of 1a,25(OH)2D3 to insulin secretion and the discovery of a new rapid, nongenomic, signal transduction process for 1a,25(OH)2D3.
Think about what drew you to this book in the first place. Do you have trouble dragging yourself out of bed in the morning? Do you experience uncontrollable sugar cravings at 3 p.m.? Nagging PMS every month? Interrupted sleep patterns? Do you get stressed out just sitting in your office? Do you have difficulty coping with every task? Bloating after meals? Skin that has lost its luster or tone? Belly fat that just won't go away? The list can go on and on, and I am willing to bet that many of you experience some of these frustrations every day. Believe it or not, these aren't just factors that make you feel bad. They are impacting your ability to lose weight!
In personalized lifestyle medicine, sometimes one person’s superfood is another person’s poison. Such is the case with oxalates, which are found in high concentrations in many presumed health foods. Once I started testing, I realized that many of my patients were experiencing the downstream consequences of excess oxalate intake, usually in the form of green smoothies … [Read More...]

androgen Dihydrotestosterone DHT multiple AR 5-DHT or DHT is a male reproductive hormone that targets the prostate gland, bulbourethral gland, seminal vesicles, penis and scrotum and promotes growth/mitosis/cell maturation and differentiation. Testosterone is converted to 5-DHT by 5alpha-reductase, usually with in the target tissues of 5-DHT because of the need for high concentrations of 5-dht to produce the physiological effects.


DHEA is the raw ingredient of many hormones and an excellent indicator of your adrenal health. Because DHEA is a precursor to testosterone, replenishing it helps the body make more of its own natural testosterone. Studies show that the level of DHEA in your body also directly correlates with longevity. Perhaps one reason is that DHEA lowers total cholesterol and LDL (i.e., the “bad” cholesterol).
Men of all ages, if you do nothing else this month - read this book! The chapter on men is a game changer for guys but the entire book is well worth your time. I am a 60-something who was suffering the classic symptoms of men my age, constant tiredness, an inability to build muscle despite five trips a week to the gym, and a lack of sex drive. This book explained the importance of testosterone and crystalized for me the path I needed to take to recapture the life I want. It also explains so clearly the role of hormones in our life that most people do not understand. Check it out - then give it to your wife to read. She'll love you for it! Really!
Stephanie is a typical high achieving young woman. Working at an advertising agency as a creative director, she’s often the first to arrive at the office. The job is demanding, but she enjoys pushing projects to the finishing line and is a self-described A-type personality. But it played havoc with her cortisol and insulin levels. Check out her story here:
The good news is that you can turn this problem around in only twenty-one days. Based on leading scientific research, The Hormone Reset Diet is Dr. Gottfried's proven step-by-step plan designed to help women of all shapes and sizes, ages, and ethnicities lose weight and feel lighter and more energetic. In seven three-day bursts, you'll make specific dietary changes, eliminating metabolism-wrecking foods—meat and alcohol, sugar, fruit, caffeine, grain, dairy, and toxins—to repair your body and reset your hormones. At the end of twenty-one days, Dr. Gottfried shows you how to develop a new personalized food code that enables you to look and feel your best every single day. In addition, this highly practical guide explores the emotional issues that drive cravings, addictions, and habits, offering insights to quench incessant hunger and get your life back. With The Hormone Reset Diet, you can finally shed the weight, feel trim and sexy, restore your hormones and health, and rediscover the body you want.
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This is a really good book and explains all the bioidentical hormones in detail. It was definitely worth reading. The only thing I didn't like was that she seemed to endorse the bioidentical pellets and she didn't like the creams. The pellets are very expensive and out of reach for some women. I have tried the pellets and I prefer the creams so I was a little discouraged when she said they don't work really well and the creams turn into estrone. My doctor disagrees with this and she also uses the creams.
I was looking for a book that gave me information about changing hormones and losing some of the weight I had gained during menopause. This was a 2 for 1 for me. I like the outline of the book in that you can jump to the sections that apply to me and skip those that don't. I didn't go for the "supplement product buy", but instead took the information about them and bought at my local health food store. I'm down 20 lbs in 3 months and still losing. I don't follow the book 100%, but the 11 day detox was a great starter. I have more energy, my mood has improved and I'm sleeping better. I highly recommend this book!
“I was (an am) unsure about how I am related to my old self, or to myself from year to year. The hormonal profile of an individual determines much of the manifest personality. If you skew the endocrine system,you loose the pathways to the self. When endocrine patterns change it alters the way you think and feel. One shift in the pattern tends to trip another.”
Dining out won’t be a problem under the Supercharged Hormone Diet. Eating out is not difficult on this diet because it essentially mirrors the Mediterranean diet – so ordering chicken and fish-based entrees and plenty of salads is fair game. You are also advised to have one meal a week that is a "cheat meal," which allows you to eat the foods you cut out.

This book is a wonderful and engaging ride through the history of hormones. Epstein elucidates while she educates us on a subject that is far more fascinating that most of us may realize. We are all a little curious about how hormones work and the role they play – growth hormones, sex hormones etc. The author takes that little bit of curiosity and pulls you into a well-researched and lucid chapter on each topic. You leave each chapter feeling so much more enlightened and educated. For example, the chapter looking at the relationship between gender, sexual orientation and hormones is a real eye-opener. Epstein has done all the work for you in terms of her in-depth research and her lucid and engaging writing style. All you have to do is sit back and enjoy the ride through the history of hormones. I highly recommend this book.


On the other hand, too much estrogen can be a major problem as well. Studies have shown that there is a link between excess estrogen and cancer. We also know that it is not just excess estrogen but an imbalanced excess estrogen that seems to be the cause. Which age group has the highest levels of estrogen? Teenagers. Yet breast cancer is virtually unheard of until later in life, because teenage girls have all their hormones in balance, including estrogen.


Four meals a day that contain four essential components–protein, carbs, fat and fiber–will slow the release of sugar into the bloodstream and ultimately limit insulin release while keeping your cortisol controlled. Most of us are familiar with the concept of eating every three to four hours, but the real importance of eating at the same time each day is often overlooked. It’s proven that simple habits lower insulin levels. For instance, I eat at 8 a.m., noon, 4 p.m. and 7 or 8 p.m. daily, and I stop eating three hours before bedtime. Eating raises body temperature, and doing so right before bed only interferes with hormones that burn fat while you sleep. 
Menopause doesn’t just hit you all at once — unless you’ve had a full hysterectomy. It comes in stages, the first of which is perimenopause. “Before the Change” focuses exclusively on the early phase of menopause: what to expect, how to control symptoms, and how to stay healthy. It also offers a self-diagnosis quiz to help you determine if you’re experiencing perimenopause.
Adiponectin is naturally released when we exercise. It is produced by our fat cells and is proven to increase metabolism, improve insulin sensitivity, reduce inflammation and reduce the risk of heart disease. It appears blueberries are the only fruit to stimulate the release of this hormone due to phytonutrients in the blueberries’ skin. The chlorogenic acid in blueberries also assist in controlling blood-glucose levels, therefore helping fat loss by improving insulin balance. A recent study showed obese people who drank one blueberry smoothie a day, for six weeks, had a 22% improvement in insulin sensitivity, which ultimately equates to better fat metabolism. Just a half a cup a day will do the trick. 
Along with advice for weight loss, Dr. Natasha Turner provides recommendations for anti-inflammatory detox, nutritional supplements, exercise, sleep, stress management, toxin-free skin care, and natural hormone replacement combined with a diet plan—all incorporated into a 3-step wellness program focused on the essentials of hormone balance for lasting health.

I liked the stories, but I was kinda looking for it to be broken down differently, more linearly, I guess. I woulda preferred a history of the major hormones from the first conception they existed through to more modern times, like I've seen in other histories of science. I felt she jumped into the middle of the history of certain hormones much of the time to get the better story and hook readers when I wanted the boring bits that got us to the middle. It is fun read with a lot of resources for further research. Just not what I was looking for

When it comes to weight loss, most people don't think about hormones. But when you develop resistance to your seven major metabolic hormones—cortisol, thyroid, testosterone, growth hormone, leptin, insulin, and estrogen—your body adjusts by increasingly raising your hormone levels and ultimately slowing down your metabolism. And a slower metabolism leads to weight gain and difficulty losing weight. The solution, Dr. Sara Gottfried contends, is to reset the efficiency of your hormones by repairing and growing new hormone receptors.
“If you’re struggling with weight and not sure where to start, look no more. The Hormone Boost, makes weight loss both understandable and doable. You’ll discover how to make each meal the right balance of protein, carbs, and fats and a blueprint with simple steps to prep your home and body. It’s the first weight loss book to address the SUM of you, not just SOME of you.” Dr. Mache Seibel, MD, bestselling author of The Estrogen Window and faculty member, Harvard Medical School
Explaining why women between the ages of 35 and 50 often experience significant changes in mood, weight, sex drive, and general well-being due to hormonal imbalances, this guide shows women how to regain control of their hormones—and their lives—and feel good again through natural means. Women who have had long-standing physical and emotional complaints written off by doctors as normal or genetic are provided with step-by-step solutions to such hormone-related problems as weight gain, fibroids, sex-drive doldrums, adult acne, depression, anxiety, irritability, chronic fatigue, and facial hair. Perimenopausal women will be able to regain control of their health by putting together a game plan for renewal—including hormone balancing and weight management plans that will help them feel better—with dramatic, life-changing results.
Although it may seem like strange advice, chase your evening meal containing your starchy carb with a small amount of tomato juice.  It’s the natural acidic quality of this tasty drink that offers us weight-loss benefits. Drinking something acidic after your meal is also known to reduce the glycemic load (or blood sugar impact), which then blunts the increase of insulin and leads to less sugar being stored as fat.
New to this Edition: Hormones, 3rd Edition is organized with two introductory chapters followed by 15 chapters on selected topics of the molecular biology of the major endocrine systems operative in humans. Coverage, for the first time of the following hormones; ghrelin, oxyntomodulin, kisspeptin, adrenomedullin, FGF23, erythropoietin, VIP and extended coverage of NO. Coverage of the hypothalamus has been integrated with the anterior pituitary because of the intimate functional and relationship between the two. Consideration of the role of hormones in cancer has been integrated into the chapters on the relevant hormones. Each of these areas occupies a unique niche in our understanding of the biological world and is part of the universality of signaling systems and how they govern biological systems.

Based on twenty hormone-supporting superfoods and twenty hormone-supporting super herbs—with modifications for Paleo, Paleo for Autoimmunity (AIP), anti-Candida, and low-FODMAP diets—these healing recipes include a terrific selection for everyday meals, from Sweet Potato and Sage Pancakes and Honey Glazed Tarragon Chicken to a Decadent Chocolate Cherry Smoothie.
"Gottfried, a beautiful Harvard Medical School graduate, board-certified gynecologist, and yoga teacher, looks like an advertisement for healthy living and convincingly pushes women to make lifestyle changes rather than immediately asking for conventional prescription drugs to treat problems such as depression. Most of her tips are solid and helpful...A valuable title."

“As a Life Coach and Certified Nutrition Coach, I see clients daily who are suffering with issues that are within their control. Most people do not understand that they have the power to change their lives! My purpose in life is to help as many people as possible reach their greatest potential physically, emotionally and spiritually.” Valerie Childs, #1 Best Selling Author, Certified Life Coach, Certified Nutrition Coach

EPSTEIN: We really are. And if you think, endocrinology is a pretty new field. I mean, in 1900, where - my grandma was born in 1900. I don't think of that as ancient history. The word hormone didn't exist. And to think that in 1970 when she was diagnosed with Addison's disease, a hormone issue, they went from by her birth not even having a word for this thing to 1970 they could measure her hormone defect down to a billionth of a gram. So we've made huge strides, but it's still a young field. We still have a lot more to go.
We live in a culture of partial truths when it comes to food and alcohol. We tend to exaggerate our assets and minimize our liabilities. I used to do it too. I would go out on a Friday night and feel like a rock star after a few drinks, and not be honest about the bad behaviors and experiences that followed: the munchies and overeating, the unkind comments that I made … [Read More...]
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