The following can result in hormonal imbalances: Glandular problems like thyroid, pituitary and hypothalamus glands problems. These glands are the primary glands that are responsible in creation and production of reproductive hormones. They can be affected by birth-control pills intake, stress and diseases like hypothyroidism. Once problems are encountered in either of these glands, an imbalance will prevent complete ovulation process to take place, thus the difficulty in conception.
Maca- Maca is an adaptogenic herb, meaning it can adapt to find and serve the needs of your body.  It can increase your energy by supporting your adrenal glands. My friend Dr. Anna Cabeca, who developed a green drink mix called Mighty Maca, says that in a before and after lab test, her client’s DHEA doubled using Might Maca.  DHEA is a precursor to our sex hormones estrogen and testosterone, so that’s great news!  Testosterone, by the way, is the dominant sex hormone in men, but women do need and want it for sex drive, muscle tone and confidence, among other things.
A: Over-the-counter (OTC) progesterone creams, usually sold as natural products or supplements, are not evaluated by FDA; therefore, they have not been approved for safe and effective treatment of medical conditions. Always read and follow the complete directions and warnings on OTC products and discuss their use with your health care provider before using them. You may also find helpful information at: //
Cruciferous vegetables are a great way to reduce Estrogen Dominance. They are rich in glucosinolates, which activate phase 2 detoxification in the liver, helping to filter estrogen metabolites from your body. This is good news for your hormone balance because it prevents estrogen byproducts circulating for too long, which can raise estrogen levels and cause hormonal havoc.
When a patient complains of fatigue or menopausal discomfort to a doctor, the typical medical workup consists of investigating thyroid function, anemia, and metabolic issues. Female and male hormones are often investigated by way of saliva or serum laboratory tests. Functional or alternative medicine practitioners commonly obtain diurnal cortisol, estrogen, progesterone, DHEA, and testosterone as baseline hormonal information through laboratory studies. While most laboratory studies are normal, DHEA and progesterone level are often low.

Other exogenous hormones. Due to large amounts of estrogens and progesterone present in commercial cow's milk, there is a significant increase in serum estrone and progesterone concentrations in consumers. All types of estrogen and pregnanediol - an inactive metabolic product of progesterone - have also been found in tested consumer urine concentrations.
Progesterone is not made in a smooth fashion. As the picture here shows, progesterone is actually released in pulses. Since most physicians only draw blood from a patient once to check their levels, and use a level of 10 ng/mL to mark the cutoff between “good” and “bad” levels, it is easy to see how the doctor and the patient can be misled into thinking that her levels are too high or too low.
Natural progesterone, which is used during fertility treatment, poses no threat to a mother and child. It is important to note that the Food and Drug Administration (FDA) does not differentiate between natural progesterone and synthetic progesterone (progestins) in its warnings. Progestins are mostly used to suppress ovulation and are found in birth control pills. They are only used in preparation for fertility treatment. In older studies synthetic progestins have been linked to a slightly increased risk of certain birth defects if used during pregnancy. The FDA has conducted a thorough review of relevant published studies and has found there is no increase in birth defects resulting from exposure to any progesterone in early pregnancy.
PCOS - (poly cystic ovary syndrome) is becoming an increasing problem worldwide and is one of the most common signs of infertility.  Anovulation takes place often which leads to problems conceiving and carrying a child.  Like endometriosis, oxidative stress is the major cause.  Anti-oxidants are essential, particularly vitamin D3, both these have successfully reversed PCOS in a number of women.
Processes, GMO soy (not so much fermented soy or non-GMO whole edamame sparingly) is best avoided when battling infertility. Regarding bio-idential progesterone creams however, there is a substance called diosgenin in soybeans and wild yams that is extracted and then modified in a the laboratory to create the progesterone found in progesterone creams. It is no longer the soybean or mexican wild yam, as a whole plant, but rather just one chemical part of the plant. Only the diosgenin from the soy would be converted to bio-identical progesterone and there would be no trace of it’s other chemical make-up such as the phytoestrogen content or isoflavones that you will most often read about related to female fertility.
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Low progesterone levels can be caused by several known factors or unknown factors. Due to the complexity of hormones, some women may have no difficulty getting pregnant but for some reason, the placenta does not create the proper levels when it should. Researchers believe that high levels of stress, poor nutrition and lack of exercise can contribute to low progesterone levels. Certain medications can also interfere with the body’s ability to produce progesterone.
HI Doniella, I’m in Europe and am 38 – I’m currently 20 weeks pregnant with my second child. my first is 4 since may and was concv very quickly but when we strated trying for no 2 in nov 2010 we had no luck. eventually in Nov 2011 I found a dr who specialises in infertility issues and worked with her and eventually became pregnant this March. (delited) i get my bloods checked every two weeks for oestogen and progesterone levels and my progesterone is low. I’m now on 2 x 400mg of cyclogest daily as my dr thinks my level is low. My last reading was 148 which makes me think that its probably 14 as you are using 2 digit numbers above. Above you refer to the use of progestone creams in the first trimester but i#m now midway in the second trimester and my dose was doubled due to last reading being so low. should i be concerned about taking pessaries at this stage of pregnacy? I’m somewhat concerned. thanks annie
I haven’t felt right since I had my baby (who just turned 2).  🙁  History:I had post partum, major stressors and major sleep deprivations.  Nursed for 13 months.  The pregnancy sugar cravings remained & were intense.  I felt like a robot for at least the first year. Def felt like I should be feeling more euphoria.  And over the course of that first year and a half, my weight decreased.  About 6 months ago or more, my appetite became very low, I had food aversions just like I did in pregnancy.  My platelets and Vit D were low but everything else checked out fine.  I have PMS, my cycles seem shorter and vary from 3-4 weeks.  For at least 2 months, I’ve had night hot flashes days before I start.  But the WORST symptoms are my heavy/foggy/fatigued head and hard to stay on task!!  Even after 8 hours of sleep.  Have not gotten my progesterone checked….some dr’s say it’s not worth it since it fluctuates.  1 was just going to put me on progesterone wo/ checking.  others say antidepressants. Thoughts?  
Dr. Hotze: When you felt well, you weren’t on all these foreign chemicals that are toxins and poisons, which poison your cells and are toxic to your body, cause your mitochondria, your power plants to produce low levels of energy and make you sicker, quicker. These things are not helpful and they’re not the cause of your anxiety, your panic attacks, or sleep disturbances. It’s a change that’s occurring in your body and it can be easily corrected by replenishing your body with natural progesterone.

Low progesterone levels can cause uncomfortable symptoms such as insomnia, dizziness, irritability, difficulty concentrating, extreme changes in mood, bloating, weight gain, muscle pain, joint pain, and urinary incontinence. Other possible symptoms of low progesterone may include frequent urinary tract infections, interstitial cystitis, changes in appetite, hot flashes, cold chills, night sweats, and vaginal dryness. Symptoms in hormone fluctuations should be brought to a doctor's attention for treatment. Most doctors will not recommend self-treatment for women who are having discomfort because many things should be taken into consideration before using hormone replacement therapy. Other health conditions and even family history will play a part in how a doctor will go about prescribing treatment for fluctuating hormones.
I’m about 5 weeks (conceived around Jan 9) pregnant and have been experiencing brown spotting for the last 5 days. My doc checked my progesterone and HCG (18 and 2100 respectively). She said she was happy with the level of progesterone but still wants to put me on an oral progesterone. My cycles have been irregular as long as I can remember and usually about a week later each month than the month before. They start with spotting for a few days to a week also. I also have arthritis (was on prednisone for ~14 years; off and on for most of last year; completely off since Oct 22). In this situation does it sound like the progesterone will be beneficial? I realize oral isn’t the ideal delivery route as your body will break it down during digestion. Just trying to get an idea of whether or not this is a good idea and what else I can be doing on top of this. Any comments/information is greatly appreciated!
IHR has treatments for a variety of conditions, including hormonal infertility, ovulatory dysfunctions, endometriosis, immunological infertility and many others. Perhaps less known is our work with individuals and couples who are considering assisted reproduction, but who are uncertain of their next step. We encourage anyone, before they make a decision, to consult with us. Currently, we are offering a FREE Hormonal Infertility E-Mail Consultation.
Rouse, D. J., Caritis, S. N., Peaceman, A. M., Sciscione, A., Thom, E. A., Spong, C. Y., Varner, M., Malone, F., Iams, J. D., Mercer, B. M., Thorp, J., Sorokin, Y., Carpenter, M., Lo, J., Ramin, S., Harper, M., and Anderson, G. A trial of 17 alpha-hydroxyprogesterone caproate to prevent prematurity in twins. N.Engl.J.Med. 8-2-2007;357(5):454-461. View abstract.
A: According to the package insert, the most common side effects of oral progesterone that occurred in more than 5 percent of patients during clinical studies were dizziness, breast pain, headache, abdominal pain, fatigue, viral infection, abdominal distention, musculoskeletal pain, emotional lability, irritability, and upper respiratory tract infection. Increased liver enzymes have been reported rarely since the drug has been on the market. For more information, please contact your health care provider. You are encouraged to report any negative side effects of prescription drugs to your health care practitioner and the Food and Drug Administration (FDA) by visiting, or by calling 1-800-FDA-1088. Michelle McDermott, PharmD
The anovulatory cycle is another sign of infertility.  This is when ovulation does not take place and is common in woman in their mid-thirties, although younger women are now also suffering from these cycles.  Excessive FSH and LH causes this.  Too much FSH and LH stimulates the ovaries which in turn make too much estrogen and testosterone.  If these four hormones are in excess, ovulation is prevented as well as the production of progesterone. Excessive use of contraceptives or stress is believed to be the cause.
I had a hormonal imbalance before I went on the depo shot since I hit puberty. Not diagnosed by a doctor but it was just very obvious. I went on the depo for 4 years and now I have been off for 7 months and my hormones coming back and I feel like a crazy person.. we’re wanting to get pregnant again so I don’t want to get on the depo again but I don’t want to feel like this anymore. Is there a solution? I know the depo affects progesterone in some way and I wasn’t sure if you could help but I had to ask!
Stopping progesterone abruptly without proper titration can also be problematic. Many have experienced a huge wave and additional surging of progesterone as it comes out of our tissues soon after abrupt withdrawal. It is a very unpleasant experience. An aldosterone surge can occur that leads to electrolyte imbalances ? which in severe cases requires hospitalization.
hey! i used to have very cold hands and feet and body aches and heavy periods. i didnt really have a lot of strength and i was usually moody. then i got married and moved in with my husband. i started feeling a lot better, my aches were gone but now my period has become much shorter, the blood is pinkish and i hardly see any tissue on my pad. its also gotten more painful. i looked up online and i think it might be because of low progesterone. i was so happy because i thought i ws getting healthier but im scared now as i want to concieve. i have always been a little underweight with high blood cholesterol but that has always been that way. please help
Hi Dr. Durnan, im 49 years old. My naturopath doctor asked me to go to laboratory and check estrone and progesterone level. They checked estradiol instead estrone and progesterone. Estradiol level is 183 and progesterone is 1.3. What that means? Should I ask lab to do test again since they check wrong type of estrogen? Does it matter?  I have all the symptoms above!
Of course, you can get lab tests. The most accurate is urine test. I like the DUTCH test but you need to find a practitioner to help you interpret the results. (You can email my team to ask for recommendations). To find a doctor in your area, here is a list of directories for you. Blood is utterly useless when it comes to steroid hormones such as progesterone.