Many women have unknowingly been estrogen dominant for years, resigning themselves to tender breasts, heavy bleeding, painful cramps or PMS mood swings and depression as the monthly consequence of “the curse.” But behind this all-too-familiar symptom picture lurks the greater health impact of hormone imbalance. “For women with undetected estrogen dominance,” writes co-author Virginia Hopkins, in the popular John Lee books on menopause, “Being put on synthetic hormones when they reach menopause is like pouring gasoline on a fire in terms of breast cancer risk.”
[Figure 40-26 on p. 538 from the NaPro textbook. Limited mucus cycles, endometriosis, ovarian dysfunction and a husband with a very low sperm count were identified in this patient who failed two previous IVF procedures. In spite of these abnormalities with proper NaProTECHNOLOGY treatment, she achieved a pregnancy and had a normal healthy baby (From: Pope Paul VI Institute).]
The consistently high physiological progesterone levels seen in pregnancy would indicate that progesterone is safe as a therapeutic agent. Progesterone therapy is commonly used in women with infertility problems due to luteal progesterone insufficiency in order to raise circulating and endometrial progesterone levels to those of the normal luteal phase.

Hi! I am 49. I’ve never taken any kind of hormonal birth control my whole life. I’ve always had easy routine periods. I’ve had three healthy children with very easy pregnancies. Suddenly about a year ago I’m experiencing horrible heavy period as with lots of blood clotting and cramping that go on for 2-3 weeks at a time. I may go 1-2 weeks without bleeding and it all starts all over again! I’m also having just about every premenopausal symptom there is! I’ve been trying lots of different herbal remedies that just don’t seem helpful much. Ugh!!! I’m really at whits end here.

I have so many of the symptoms you have listed. I have suffered three miscarriages before having my sons. I needed progesterone(shots) when I was pregnant with both of my sons(13 & 14) . Now @ the age of 44 I had a emergency hysterectomy 6wks ago after hemorrhaging on day 14 of my period. I never thought to have my progesterone tested after having my children. I will defiantly do this @ my 8wk post-op. Do you feel otc progesterone cream(organic) can be beneficial? Thanks!
Signs of a miscarriage might be a heavier period, clots and/or pain. The egg takes about 12-14 days to reach the uterus, if the corpus luteum does not maintain a high level of progesterone during this time, menstruation will take place before the egg is embedded.  This can be easily corrected by supplementing with progesterone thereby extending the luteal phase.

The reproductive endocrinologist at IHR will evaluate specific situations and perform tests in both the male and female partners to determine the cause of infertility. The physician is looking for answers to the following questions: is the female ovulating regularly, is the male producing healthy, viable sperm, are the female's egg and the male's sperm able to unite and grow normally, are there any obstacles to proper implantation and maintenance of the pregnancy?
If a woman is stressed, her body “steals” the  pregnenolone and uses it for stress hormone production instead of progesterone production.This means that other female hormones also take a hit — accounting for why some women have low hormone levels across the board — but progesterone is one of the hardest hit.  If a woman has low progesterone in her labs, it’s a pretty good bet that her body is using her resources to produce cortisol rather than progesterone.
Recently, much controversy has arisen about supplemental menopausal hormone therapy. It can either be administered with estrogen only (estrogen therapy or ET) or in a combination of estrogen-progestin therapy (HT). This treatment is used to alleviate progesterone side effects and to prevent bone loss. HT prevents build up of the uterus lining. ET stimulates growth of the lining. This is a possible risk for uterine cancer and should only be undertaken after a hysterectomy. What is advised for women is to receive the lowest dose for the shortest amount of time to correct the problems. More research is being done of the ramifications of this disease and the long-term effects on women. A woman should have a continuing conversation with her health professionals about the treatment she should be undergoing and the risks she faces with that treatment.

I have premature ovarian failure (now 35 years old) and have been on bioidentical hormones for 8 years now. I am using estrogen cream everyday (Biest) and for 2 weeks out of every month, I take a 200 mg compounded progesterone troche and my progesterone level is only 2.5! I have tried every imaginable combo of bioidentical progesterones (both oral and troches) and can’t get my level up. I used to have higher progesterone levels and would have a period after taking the progesterone, but now absolutely nothing. Would you think something has changed in adrenal health or gut health for my body to just stop responding to my hormones? It used to work and just doesn’t any longer. Any tips???? Thank you very much.
I started to get pain in my ovaries last September, and started trying to conceive in Feb. In April I had a miscarriage and the scans showed I had a cyst on each ovary. I keep going back to get help from doctors as I am constantly in pain from persistent cysts but they say it’s natural and send me on my way still in pain. It’s nearly been a year worth of pain and I just want rid of these recurring cysts.

Low progesterone levels can be caused by several known factors or unknown factors. Due to the complexity of hormones, some women may have no difficulty getting pregnant but for some reason, the placenta does not create the proper levels when it should. Researchers believe that high levels of stress, poor nutrition and lack of exercise can contribute to low progesterone levels. Certain medications can also interfere with the body’s ability to produce progesterone.
Progesterone is made from the cells that surrounded the egg during its development. They are called granulosa cells. The cells make up the wall of the cyst that contains the egg. This type of cyst is called a follicle. As the egg develops, the follicle grows and the granulosa cells increase in size and number. Before ovulation (release of the egg), these cells produce mostly estrogen. After ovulation, they still produce some estrogen but a lot more progesterone. After ovulation, the follicle cyst is called a corpus luteum cyst.
The use of birth control pills in teenage girls has the potential to raise their risk of breast cancer. It is well established that when girls between the ages of 13 and 18—and to a lesser but still significant degree, up to the age of 21—use birth control pills, their risk of breast cancer can increase by as much as 600 percent. To put it plainly, the earlier a girl begins to use contraceptives, the greater her risk of breast cancer. This may be because the younger the girl, the more undeveloped her breast tissue, and thus the more vulnerable it is to the synthetic hormones contained in the pill. Furthermore, contraceptives work by inhibiting ovulation, which significantly reduces progesterone production and its essential estrogen balancing effects. This is a situation many young women find themselves in: ripe for symptoms of estrogen dominance and vulnerable to long-term risks for breast cancer. (Excerpted from What Your Doctor May Not Tell You About Breast Cancer: How Hormone Balance Can Help Save Your Life.)
I’m trying to conceive for the third time. Twice I have been pregnant and twice I have had miscarriages at 6 weeks. I have had a laparoscopy and been told I have mild endometriosis. My Doctor will not give out progesterone as he belives there is no benefit to it. I have a BMI of 21, I am following a diet to help endometriosis and my cycle is every 26 days. I want to use progesterone so I feel I am doing everything to stop a miscarriage occuring for the third time and I’m concerned that it could cause harm if I use it wrongly. I feel cream would be the best. Could you advise if I could use it as a precaution and would that be safe for the baby and if so can I get this cream in the UK.
Fertility or menstrual problems: Estrogen grows the lining of your uterus to prepare it for conception (remember that grass analogy above?). But progesterone also has an important role – to ensure that the lining remains there for roughly 14 days after ovulation (the luteal phase) in case you become pregnant. If you conceive, progesterone rises. If not, progesterone levels drop again causing the shedding of the uterine lining which we know as menstruation.