The use of birth control pills in teenage girls has the potential to raise their risk of breast cancer. It is well established that when girls between the ages of 13 and 18—and to a lesser but still significant degree, up to the age of 21—use birth control pills, their risk of breast cancer can increase by as much as 600 percent. To put it plainly, the earlier a girl begins to use contraceptives, the greater her risk of breast cancer. This may be because the younger the girl, the more undeveloped her breast tissue, and thus the more vulnerable it is to the synthetic hormones contained in the pill. Furthermore, contraceptives work by inhibiting ovulation, which significantly reduces progesterone production and its essential estrogen balancing effects. This is a situation many young women find themselves in: ripe for symptoms of estrogen dominance and vulnerable to long-term risks for breast cancer. (Excerpted from What Your Doctor May Not Tell You About Breast Cancer: How Hormone Balance Can Help Save Your Life.)
A few days ago, I saw a progesterone cream that a friend of mine gave me a couple of years ago in my cabinet, and decided to just use it up, I didn’t think much of it nor expect anything but this week I suddenly feel energized again and wake up without the alarm clock and ready to go, even if it’s raining or cold. So I started wondering if maybe my progesterone levels were low and I didn’t know it and this cream is helping me. My luteal phase also had shortened by 4 days, I’ll see in a month if it goes back to 4 weeks. Thank you for all the info!
Low progesterone during pregnancy can be one cause of recurrent miscarriages. Progesterone is responsible for creating a healthy environment in the womb by maintaining the uterine lining. It also reduces the chances of blood clots and the immune system responding to the fetus as if it was a foreign substance. Progesterone is one of the main pregnancy hormones.
Green tea helps with estrogen metabolism, which is critical when dealing with estrogen dominance and lowered estrogen levels are associated with fewer incidences of cancer, especially breast cancer.  In one study, Japanese women who drank green tea daily had up to 40% urinary estrogen levels as compared to women who drank green tea only once per week.(4)

So estrogen becomes the dominating hormone which can lead to the buildup of the tissue in the inner lining of the womb. So the periods become longer, heavier. They get cramping, breakthrough bleeding. This can cause a host of problems with the premenstrual symptoms of fluid retention, weight gain, headaches, breast tenderness, fibrocystic breast disease and other various symptoms. So, progesterone is a very important hormone that inevitably declines as a woman ages until a woman hits menopause, whether she quits making from her ovaries any estrogen or progesterone at all.

Hi. I would love some advice. I have two healthy little boys and had no problem conceiving or carrying them. My partner and I decided to try for number three and I came off Cerazette last September. Since then I have had two early miscarriages in the last 3 months. I am going to have blood tests to check all of my levels. Do you think that as Cerazette is a progesterone pill, my own levels could have dropped and then not risen again once I stopped taking it. I could be clutching at straws but would appreciate your thoughts.
Clinical research on the effects of weight gain and levels of progesterone have found that high levels increase weight. A study published in the journal Physiology & Behavior found subjects that were treated with progesterone alone to treat symptoms of menopause increased weight. Using a combination of both estrogen and progesterone didn’t result in any weight gain.15
I’ve never been tested during my cycle, but was put on Progone B that I was supposed to take from the date of ovulation until the first day of my period, to try and boost things. I never had any kind of … success with that. The next time we decide to try, which won’t be for a couple of years, I want to make sure that I have implemented more natural ways of balancing my progesterone…
What happens is as a woman moves towards menopause, she’ll have multiple anovulatory cycles. Maybe not quit ovulating altogether and that’s when she gets these heavy, heavy periods. She gets fibroid developing in her womb. She ends up going to the OBGYN to help her and he’s always got an answer and it has to do with a scalpel or a knife. Hysterectomy is always his answer. But the reason we had that problem is because the hormones are declining and they’re imbalanced and the progesterone is deficient.
Stacey B: Well, Dr. Hotze, thank you for being such a visionary, too, and recognizing years ago the positive impact it would have on women. Now you know why I was so excited at the beginning of this podcast about the benefits of progesterone. It’s so easy. If you’re out there thinking, “Do I have symptoms of low progesterone? Would that be able to help me?” So easy to go to our website HotzeHWC.com. That’s H, O, T, Z, E, H, W, C.com and take our symptom checker. Then you can also call our office for a free consultation at 281-698-8698, as well. It’s a pleasure having you here today. We are so glad you joined us today here at Dr. Hotze’s Wellness Revolution.
Postmenopausal women and children tend to have the lowest progesterone level and often have a progesterone deficiency. Adult males have a similar progesterone level to that in women during the follicular phase of their menstrual cycle. When a woman ovulates, the level of progesterone in her blood more than doubles. During pregnancy, her progesterone level goes up by one to two hundred times.
Dr. Hjort notes that when progesterone seems to work, it’s possible that the patient was going to sustain the pregnancy anyway. Because there is solid research on both sides of the debate, she believes there is something science hasn’t figured out yet, and progesterone just happens to help with whatever underlying condition(s) there may be. It could well be that the progesterone truly solves the problem; but the science isn’t yet certain of what that “problem” is.
So, those can be solved, a progesterone deficiency can be solved early in a woman’s life as soon as she begins to have these symptoms, premenstrual symptoms of mood swings, fluid retention, headaches, and breast tenderness, that she gets premenstrually and these heavier periods. As soon as that happens, start taking progesterone day 15 through 28 to balance out the estrogen. That can be a godsend for a woman.

What happened when we put them on the progesterone, they never had any postpartum blues. They never had any…none of them in 18 pregnancies, had postpartum depression. So, we encourage women at our office here at the Hotze Health & Wellness Center that are of childbearing age and they are pregnant, to make sure that they take natural progesterone after they have that baby, because there’s going to be a precipitous drop and that’s what leads to the postpartum blues or the postpartum depression.
I have had 2 miscarriages already and I am now 15 weeks pregnant with twins. I was taking Progesterone 200mg every night my mouth until just last week when they tested my progesterone again and found that my body was doing well on it's own. This is the farthest I have been able to make it in all 3 of my pregnacies and with twins no less so I am very optamistic :)
Oh, I also have (especially lately) stupid bad sugar cravings and have been really fatigued. My memory kind of quit on me back when I was 17.  Every dr I have tried to go to until now, and currently this dr is a holistic ms, has insisted on putting me on a low dose anti depressant. Ok if it is major depressive disorder or bi-polar and I have to, then fine, but no one would do any kind of tests to see if I had an actual reason for the depression symptoms! 
lastly, I started working out again finally (had been way too tired / no energy to do so before) about 2 months ago.   In an effort to gain weight, eat healthy again and feel better.   I have started gaining weight and my food appetite is back and no more sugar cravings.  However….the fatigue, foggy headedness, can’t concentrate, and a few days even blah or down…….I want that to go away!!!  Thanks!!!  

My husband and i live in australia, i am 31 & he is 33 and we are both a healthy BMI and we have a 3 year old daughter that was conceived naturally and had a natural birth. We have since been TTC for 2 years with only a “successful pregnancy” ending in early miscarriage at around 6-7 weeks. my cycle has slowly increased from around 23/24 days to now a 26/27 day cycle. i have completed a day 21 progesterone test twice, the results were 17 & 24 which i wonder if that is high enough to sustain a pregnancy, my day 2 FSH was 7.2 & my E2 was 138. this month my HyCoSy came back showing a healthy uterus, clear tubes & good ovaries with 6 eggs maturing in one ovary & 8 eggs maturing in the other at cycle day 8 and my AMH was 9, my husband semen analysis was good, so to date it seems to be unexplained fertility but from my zig zag looking bbt charting it looks like something is out! for quite some time i have been feeling extremely light headed like i could pass out, and foggy in the back of my head and finding it hard to concentrate, fatigued, low libido, recently started having allergies to flowers when i never have in my life, also having night sweats and being far more emotional than i usually am yet every time i see a doctor about this they do blood tests and give no answers and say if nothing comes up they can only assume its panic attacks.. but i had been wondering if its by hormones causing me all this grief and after reading your article it seems to have possibly shed some light! 
Hi, thank you for this Info!! I found out my husband and I are pregnant after having a miscarriage 2 months ago. I had blood work done and I have extremely low progesterone levels and may quite possibly lose this baby. We think that may be the cause of my other 2 miscarriages, although we do have 1 daughter. Can low progesterone lead to uncontrollable irritability? I know it can lead to mood swings. I was on progesterone birth control for a long time, and the high levels of progesterone made me extremely difficult and moody. I’m wondering if I just need a more balanced progesterone level. Your article helped me understand jus how much my extreme stress is hurting my body!! Thank you!

My husband and I have been trying to conceive via surrogacy as I had an endometrial ablation in 2006 due to heavy menses. Due to the surgery, my mense has not returned and therefore never know when I’m ovulating. My eggs have been deemed “normal” at retrieval and the embryos were of very good quality. Our surrogate was fully checked and her hormone levels and endomentrial lining were a “go” from the clinic. We had 2 failed transfers (April & July 2013). I’ve always had problems with my progesterone levels (probably since high school) and didn’t find out until February 2013. My naturopath put me on a bio-identical progesterone cream and my hormone levels increased to the point where my low progesterone symptoms vanished! I was in heaven!! Once I started taking the fertility meds for my egg retrieval I had to stop my progesterone cream. Since the failed transfers, I started back on the progesterone cream and my hormone levels have not increased one bit! I’m very frustrated and have another naturopath appt next Friday, November 8. I’m on a special hormone diet to help with the low progesterone symptoms (too many to list) but nothing has helped. So, I’m wondering if my progesterone levels are to blame for the embryos not implanting into a perfect environment in my surrogate?? Should I start thinking of donor eggs instead?? What are your thoughts?


Hi, i was diagnosed with depression and sent to a physchologist back in feb this year. I was always tired, moody, irrational, low to no libido, stressed, heavy periods,  pain in my lower abdomen, crying easily and a lot, unable to concentrate, no motivation to get stuff done. After a number of therapy sessions I was given the all clear in May. It was determined that my depression was a result of relationship issues. I’m 33years old have a 2year old son and work full time. Shortly after being diagnosed my fiancé   ended our relationship. In June I moved out with my son. I’m still getting all of the symptoms above now and my moodiness and irrational thoughts occur more during my period. I think my relationship problems were because of my symptoms above and I’m looking for reasons why I’m still having these issues when I’m no longer with my ex. I was reading the above symptoms and in my head going… Yep yep yep… Thinking I should get my hormone levels checked… What can I do to help if I do have low progesterone though?? 
If you have had one or more of these issues, ask your doctor about looking into a progesterone test. Progesterone therapy could be the answer to an issue that was misdiagnosed or left unexplained, but that also doesn't mean it's a cure-all. Luckily, the risks of supplementing with progesterone are “probably low, if anything at all,” says Dr. Hjort, at least in the short term. Common side effects include mild headache, mild nausea, dizziness, and breast tenderness. Time and research will tell if there are long-term side effects.

I have a lot of these symptoms. I haven’t been diagnosed for sure yet, but I believe that my body is being affected by low progesterone. Around day 4 of my cycle, I start getting depressed and it lasts about 3-4 days (day 6-7 of cycle being the worst). My mood seems to start improving on day 8 with it back to normal by day 9-10.  My face has also been breaking out, I’ve been tired at different times of my cycle, and I have virtually no libido.  This has all started happening since I stopped the pill (Ortho cyclen) in August. 
A: I have reviewed the available literature on your question regarding progesterone. The physiological action of progesterone in this case would be to shrink the fibroid, which means that it would be reabsorbed into the body. The progesterone would not cause the dark discharge and would not cause the fibroid to "dissolve." If this continues much longer, I would recommend that you make an appointment to see your physician. You may want to view the information on uterine fibroids on Everyday Health at //www.everydayhealth.com/columns/health-answers/a-new-understanding-of-uterine-fibroids/ For any immediate concerns, consult your physician. Joseph Hall, RPh
A: A study published in the journal Obstetrics and Gynecology in 1999 found that natural progesterone cream significantly reduced hot flashes compared to the placebo group. In The Wisdom of Menopause, Dr. Christiane Northrup says that a 2 percent progesterone skin cream works in about 85 percent of perimenopausal women. A little as 1/4 tsp once per day can ease hot flashes. Make sure that you read the labels of natural progesterone cream products careful as there is great variability of progesterone content. Some creams contain less than 5 mg progesterone per ounce, whereas others contain more than 400 mg progesterone per ounce. This can be obtained over the counter or by prescription. I have not found any studies that indicate it should be discontinued over a certain time frame.
While a one-time overdose of natural progesterone cream is rare (except in people who are very weak or sensitive), the body?s ability to handle excessive progesterone can be overwhelmed over a long period of time. Progesterone side effects and toxicity are eventually triggered due to a cumulative saturation effect of progesterone in the cells. The common belief that natural progesterone is ?harmless?, even in high doses, is quite na?ve.
Hi – I have short, light periods and an ovulation cycle of 26 days (24 when I’m really stressed). In the 9 days leading up to my period, I get dark brownish discharge (no more than usual, just brown). My OB/GYN said this means I’m not producing enough progesterone, but every time I’ve gone on a progesterone pill, it didn’t do anything about the spotting and only made me gain weight. The only thing that’s helped regulate my cycle and get rid of the luteal phase spotting was going back on birth control, but I’m trying to get pregnant so that’s not an option. I’m trying to get enough sleep, keep my stress minimal, eat healthy (fruits, veggies whole grains, fish, etc), and exercise regularly – but it doesn’t seem to be helping. Should I try DIM? Are there any other suggestions that might help? Apparently this luteal phase spotting is really common and it seems like doctors know shockingly little about how to solve it. Thanks in advance.
The progesterone prescription products that have been approved by the Food and Drug Administration (FDA) are LIKELY SAFE for most people when used by mouth, applied to the skin, applied into vagina, or injected into the muscle with the advice and care of a healthcare professional. However, progesterone can cause many side effects including stomach upset, changes in appetite, weight gain, fluid retention and swelling (edema), fatigue, acne, drowsiness or insomnia, allergic skin rashes, hives, fever, headache, depression, breast discomfort or enlargement, premenstrual syndrome (PMS)-like symptoms, altered menstrual cycles, irregular bleeding, and other side effects.
I have many of these symptoms, I am currently on BHRT and take a topical estrogen and Rapid Dissolve Tab of Progesterone for 4 years now after a hysterectomy with one ovary removed… Throwing me into a downward spiral into Menopause. Yikes!! and I am still experiencing some symptoms of imbalance. I have mentioned this to my Physician and he always looks at my labs and tells me I am at a good range. I am getting frustrated with the continued symptoms, he is a highly trained bioidentical hormone doctor. Not sure what the answer is at this point. Not too many  bio doctors to trust in my area. 
I have a question — I’ve been struggling with what I’ve been told is Hypothalamic Amenorrhea for a few years now. I’ve lost and regained my period several times due to fluctuations in weight, calorie intake, and exercise, but have always managed to get it back by changing my lifestyle. I had my period in January 2012, then didn’t get it again for an entire year. My gyno did bloodwork which was normal, except for low hormone levels (also had an ultrasound to check for cysts on my ovaries, result was negative.) In November of last year I took provera and had a withdrawal bleed, but no period in December. I then got my period this January (same time that I did last year, while I was on winter break from school) after further reducing my exercise, mainly cutting back on running. However, I haven’t gotten another period since.
I have been having severe headaches for 6 months. It has become increasingly worse and almost impossible to function with daily life task. I have been to the doctor and have tried everything from antibiotics, steroids, over-the-counter medicine and migraine medicines, etc. I have had ct-scans and MRI’s. I have expressed my feelings and that I did not feel that something was right. I was beginning to think that something was seriously wrong with my brain. I was a previous depo-provera user for 10+ years and had to stop using it because of weight gain. As soon as I stopped the head aches started. No one caught it. I have been to primary, specialist, and gynecologist. Since coming off the depo a year and a half ago I still have not had a cycle so my doctor gave me a  medroxyprogesterone to see if it would help to get my cycle started. I took one pill last night and for the first time today I do not have a headache. For the last 8 days I have had one all night long. It is gone. Is there something that I can do to get this level? I wish my doctors would have listened to me. I have been in pain for 6 months and if they would have listened to me we could have fixed this a long time ago.

During childbearing years, progestin reduces the risk of endometrial cancer. Someone who has polycystic ovary syndrome or is over weight or under weight may need to take birth control pills to counteract the progression of the disease. On average, women enter menopause at age 52, at which time they may experience high progesterone levels. The progesterin may fluctuate wildly, increasing and decreasing. Periods become irregular and hot flashes may occur. That's a time when health professionals may recommend some type of therapy to counteract the progesterone side effects, whether it is low or elevated. The normal therapy is administering low doses of birth control pills. This is a time when the body produces only a fraction of the estrogen it once did. A balance between estrogen and progestin is necessary for good health. For women who have problems with these therapies, the medication may be administered only four times a year.

Progesterone is a hormone found in men, women and children. Everyone needs a small amount of progesterone for good health and longevity. Women of reproductive age need (and produce) the most. Progesterone plays an essential role in a woman's reproductive cycle and her ability to have children, and if she does not produce enough and has low progesterone many serious problems can occur.


Progesterone is found in many different forms and can be taken either by mouth if you’re prescribed to take progesterone pills, by intramuscular injections if the doctor recommends you to mix progesterone with the oil, or through the skin, if you choose to use progesterone cream. Commonly, progesterone creams are considered to be more effective since they don’t get lost through the liver and quickly get absorbed through the skin. Still, this is where the rule “the more the better” isn’t applied, for if you use more cream than recommended, you can achieve an effect opposed to the desired one and cause hormone imbalance. The compounds with the oils used on different women may also lead to very opposite reactions, therefore, the medication should be prescribed individually and, as we’ve mentioned above, by a professional. We will take a closer look at the treatments, including those that can be done in a natural way, further in the article. For now, let’s identify the common symptoms that tell of the progesterone deficiency and learn some basic causes that lead to the hormone imbalance.
The correct levels of progesterone must also be in the right balance with estrogen to regulate your menstrual cycle. Abnormally high levels of progesterone can be caused by abnormalities in your menstrual cycle, dysfunction with your adrenal glands, or being under too much stress. Some of the warning signs that your progesterone levels are constantly too high are fatigue, difficulty losing weight, and decreased sex drive.
5. Low libido, fatigue, foggy thinking –  most often women come in to our clinic complaining of these symptoms post-partum but many women in their 30s and 40s, regardless of their child-bearing status, will start to experience an energy, sex drive, and mental shift with a drop in progesterone. Less than keen on sex? Feel like having an afternoon nap? Can’t remember names or words as well as you once did? Please ask your doctor to test your progesterone in your next check-up.
When I was pregnant was the first time Ive ever felt emotionally stable.  It makes me wonder if I normally have a progesterone deficiency. I’m normally moody, reactive, anxious , depressed, overweight, crave sugar, have dry skin, brittle nails and thin hair. I lost 20 pounds while pregnant and didn’t have the same cravings I do when not pregnant.  My husband even said I’m much nicer when I’m pregnant! How do I know if I indeed have a hormone imbalance? I had my thyroid levels tested two years ago and they were normal. I’m about to start taking the mini-pill for birth control, could this help balance things out? 
Progesterone level: Progesterone increases on the day of ovulation and peaks seven days later (midluteal phase). A normal blood level around that day was used as standard evidence of normal ovulation and corpus luteum function. However, a 2016 paper published at NCBI notes the test is not reliable for diagnosis of low progesterone because the hormone secretes in pulses. Blood levels can range widely, depending on when it is performed in relation to the timing of the pulses.
The consistently high physiological progesterone levels seen in pregnancy would indicate that progesterone is safe as a therapeutic agent. Progesterone therapy is commonly used in women with infertility problems due to luteal progesterone insufficiency in order to raise circulating and endometrial progesterone levels to those of the normal luteal phase.
Because of the lack of evidence for improved pregnancy outcomes, the ASRM Practice Committee Opinion does not advise luteal phase hormone therapy with HCG or progesterone unless you are undergoing an assisted reproductive technology (ART) procedure, such as in vitro fertilization (IVF). Pituitary suppression drugs used during ART cycles can interfere with corpus luteum function and progesterone production. In this situation, treatment increases pregnancy rates and reduces miscarriages.

I’m sorry you are having difficulties with the thought of getting off HRT. I know this may sound new to you but healing your digestive system will help with anxiety and depression. Please watch Magdalena’s free workshop on cooking for balance on how to balance hormones with food. You will learn so much and getting off HRT won’t seem so scary anymore. http://www.cookingforbalance.com
×