Progesterone may also appear low in cases of estrogen dominance. What this means is that there is a higher than normal level of estrogen, and not enough progesterone to counterbalance it. In these cases, the actual progesterone level may be normal but there are symptoms of low progesterone. The key here is to support estrogen breakdown and detoxification and reduce exposure to estrogen-mimicking substances like plastics (phthalates, BPA), pesticides, hormones in meat or dairy and other chemicals found in personal care products (such as parabens and DEA).

Progesterone pills – doctor prescribed, these pills can be found as either bio-identical or synthetic, so talk to your doctor about the version they are writing a prescription for. In my own personal experience, as well as hearing from thousands of women throughout the years, I’ve found that pills are one of the least effective ways to take progesterone as the digestive system has to break it down and it gets processed by the liver before being used. It simply made me bloated and did nothing for hormone balance. Some women have had decent results with the pills, so if that’s all your doctor will do it may still be worth trying!
I have premature ovarian failure (now 35 years old) and have been on bioidentical hormones for 8 years now. I am using estrogen cream everyday (Biest) and for 2 weeks out of every month, I take a 200 mg compounded progesterone troche and my progesterone level is only 2.5! I have tried every imaginable combo of bioidentical progesterones (both oral and troches) and can’t get my level up. I used to have higher progesterone levels and would have a period after taking the progesterone, but now absolutely nothing. Would you think something has changed in adrenal health or gut health for my body to just stop responding to my hormones? It used to work and just doesn’t any longer. Any tips???? Thank you very much.
Perimenopause is the ten year period before menopause during which your ovarian function is declining.  For some women, they are still getting a period pretty regularly and feeling pretty good.  For others, this ten year period can be tumultuous.  After learning about stress and nutrition above, I’m sure you could guess these things could play in to a rockier perimenopause.
In any case, there is much women of all ages can do to rebalance progesterone and overall hormone levels to avoid becoming estrogen dominant. First, we can work with a provider to test our hormone levels for imbalances. If testing reveals estrogen dominance, we can take steps to restore the natural equilibrium by rebalancing with bioidenticals—hormones derived from plant compounds that are made to be identical in structure and function to those our body makes naturally.
Cancer-causing toxins accumulate in body fat—the more body fat the more room for stored toxins. We can excrete these by losing weight and eating fiber that binds up toxins and escorts them out of the body. Fat cells also contain the enzyme aromatase, which converts testosterone to estrogens. This is why overweight and obese women have more estrogen. The more estrogen produced in the breast tissue, the more chance of stimulating the growth of breast cancer cells. Fat also produces substances called cytokines that are inflammatory in nature. A whole host of diseases including cancers of the breast and prostate are aided and abetted by silent inflammation.
Low progesterone is associated with, but does not cause, infertility. There is no effect on fertilization of your eggs or the implantation of an early embryo in your uterus. However, low progesterone can interfere with further development of your embryo and fetus after implantation. This can lead to a nonviable pregnancy or miscarriage during your first trimester.

Using a NaProTECHNOLOGY approach for the treatment of infertility can be highly effective and even more effective than current approaches to infertility.  In Figure 51-5, a life table comparison of the effectiveness of NaProTECHNOLOGY (in blue) with a similar non-NaProTECHNOLOGY approach taken at Johns Hopkins University is shown.  The success rates are clearly better using the NaProTECHNOLOGY approach.
Hi. I have been trying for 5 years to conceive with my husband. I have been blood tested numerous times as well as having a lap and dye test. My progesterone has come back at 10.5 and the lap and dye showed twisted fallopian tubes. I have had tubal surgery yesterday to save my tubes which was a success but how do I know if my progesterone is still low and  what can i do about it to help me get pregnant? I still have most of the symptoms you describe above. 

Progesterone is one of the major female hormones produces by the ovaries. The other hormone is estrogen and the two hormones work together to control a woman’s menstrual cycle. Doctors often prescribe progesterone as hormone replacement therapy for menopausal women. Progesterone is available in pill form, as a topical gel, as a vaginal insert or as an oil. Due to the way the body uses and produces hormones, it may be difficult to have a one-time overdose of progesterone. Prolonged use can cause several side effects.

Luteinizing Hormone (LH) stimulates the ovaries to release an egg and start producing progesterone – a hormone that prepares the uterine environment to nurture a fertilized egg. LH can be found in a woman’s urine just before ovulation occurs. Over-the-counter tests that help predict ovulation measure this increase of LH via a urine sample. Urinary LH testing is commonly used to help time intercourse in order to improve pregnancy chances.
A little heads up though. Most doctors are so set in their understanding of the 28 day model of a woman’s menstrual cycle that explaining this to them will be like banging your head on a wall over and over again. No matter how many times you try to explain it, or even if you bring in your charts and show your doctor, you’ll be told to come in on day 21 of your cycle.

If your doctor finds that your progesterone levels are lower than normal, he or she may recommend that you take a conventional synthetic hormone replacement. Conventional hormones are an option, but there are some issues that are associated with this route. Be sure to discuss all of your option with your doctor and consider any possible side effects that you may experience.

In my opinion having 2 M/C's does not mean that you are having issues. M/C are generally the bodies way of dealing with an issue. I had several misscarriages and they were not caused by fertility issues. As it turned out my husband and I were incompatible and after several tries we finally had our son. Talk to your Dr before making assumptions that the m/c's were nothing more than your body making the correct choice for it.
Oh, I also have (especially lately) stupid bad sugar cravings and have been really fatigued. My memory kind of quit on me back when I was 17.  Every dr I have tried to go to until now, and currently this dr is a holistic ms, has insisted on putting me on a low dose anti depressant. Ok if it is major depressive disorder or bi-polar and I have to, then fine, but no one would do any kind of tests to see if I had an actual reason for the depression symptoms! 
[Figure 40-23, p. 536 from the NaPro textbook. This diagnostic grid for both female and male diagnosis in patients with primary and secondary infertility is shown following complete NaProTECHNOLOGY evaluation (N=660). The diagnoses are presented according to their presentation as the most important or secondary diagnoses (From: Pope Paul VI Institute).]
Dr. Hotze: We had Carolyn Dean on. She wrote the Magnesium Miracle and I had Stacey read this several years ago. I said, “You know, Stacey. She had had problems with migraines.” I said, “Have you tried progesterone?” “Yeah, but it didn’t really work.” “Well, maybe it’s magnesium. Here. Dr. Dean talks about magnesium being a common cause of migraines. Why don’t you try it?” How often were you having migraines?
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A: Drugs can cause weight gain in several different ways. Some can increase appetite or make you crave certain types of foods like those high in carbohydrates or fat. Other medications may slow down metabolism or cause fluid retention. However, the effect of prescription drugs on body weight is complex. Some drugs have no effect on weight, while others cause weight gain or weight loss. Also, the same medications can cause weight gain in certain individuals and weight loss in others. There are also drugs that initially cause weight loss and then lead to weight gain with long-term use. Most prescription medications associated with changes in body weight affect the central nervous system. These include antidepressants like monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, and selective serotonin reuptake inhibitors (SSRIs). Mood stabilizers (lithium, valproic acid), antipsychotics, and anticonvulsants have also been linked with weight gain. Other drugs that have been reported to cause weight gain include diabetes medications (insulin, sulfonylureas, and thiazolidinediones), antihypertensive drugs, certain hormonal contraceptives, corticosteroids, antihistamines, some chemotherapy regimens, and antiretroviral protease inhibitors. Progesterone has been reported to possibly cause weight gain or weight loss. If you think a drug you are taking is causing weight gain, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Laura Cable, PharmD

Obesity leads to the reduction of SHBG (sex hormone binding globulin) a protein that binds estrogen levels and keeps them out of circulation. When these levels go down, estrogen levels go up, become active, and thus stimulate the growth of breast cancer cells. Over one hundred studies have investigated the links between obesity and breast cancer. Taken as a whole, their findings strongly indicate that overweight or obese women have a 30 to 50% great risk of postmenopausal breast cancer than leaner women. It is known that women who continuously gain weight throughout life have a higher risk of breast cancer.
If the woman does not become pregnant, the corpus luteum breaks down, lowering the progesterone levels in the body. This change sparks menstruation. If the body does conceive, progesterone continues to stimulate the body to provide the blood vessels in the endometrium that will feed the growing fetus. The hormone also prepares the limit of the uterus further so it can accept the fertilized egg.
Unfortunately, for most this honeymoon does not last indefinitely. While some people continue to do well on such a program, many report this multiple hormone replacement approach gradually loses effectiveness over time. Those who are already in advanced stages of adrenal fatigue prior to beginning such program are particularly vulnerable. Over months or years, there is a slow but gradual loss of the positive clinical outcome as compared to the initial benefit. As time progresses, many return to their doctor for more help.

Cancer-causing toxins accumulate in body fat—the more body fat the more room for stored toxins. We can excrete these by losing weight and eating fiber that binds up toxins and escorts them out of the body. Fat cells also contain the enzyme aromatase, which converts testosterone to estrogens. This is why overweight and obese women have more estrogen. The more estrogen produced in the breast tissue, the more chance of stimulating the growth of breast cancer cells. Fat also produces substances called cytokines that are inflammatory in nature. A whole host of diseases including cancers of the breast and prostate are aided and abetted by silent inflammation.
[Figure 40-23, p. 536 from the NaPro textbook. This diagnostic grid for both female and male diagnosis in patients with primary and secondary infertility is shown following complete NaProTECHNOLOGY evaluation (N=660). The diagnoses are presented according to their presentation as the most important or secondary diagnoses (From: Pope Paul VI Institute).]

Now ive noticed even before the sterilization, I get low, very low almost collapse low, energy during the month, and is worse now I do get period, like low blood sugar, my blood test was normal, I asked the doctor for a hormone test he said I was too young? im 41, as I said it could be the menopause early like my mum had?? now im thinking maybe I have low progestone? its driving me nuts, as there is no warning, and I cant function properly, had confusion, memory loss, no balance, blurry vision, disorientation, now the doctor thinks im a hypercondriact, and to top it all hes Italian and im English!!! as I now live in Italy, he said its the move from London…….damn cheek!!! yes I have become irritable and yes I do fell like swinging for him lol!!!
I’ve got a question… I had a miscarriage in ’05. Then had a very healthy pregnancy in ’08. Since then this past Feb we tried again and I suffered a horrible miscarriage. Last month I had yet another, luckily this one was quick and my body actually took care of it all. If I have low progesterone, could this cause the miscarriages? And if so, should I be tested for this before we try to conceive again?
Dr. Hotze: Remember, progesterone is important to help prevent infertility and help maintain good pregnancies, and to help resolve PMS, which is caused by low progesterone…to help prevent cancer, to strengthen thyroid function, to strengthen bone health, help you with your sleep, help you with fluid retention and weight gain…to help you heal brains particularly if you had an injury. It can be used for that. It’s very important for moods, anxiety, and depression. It can help relieve that because it calms you. Finally, if you’ve got migraines and headaches, it can be a Godsend. So, that’s one of the key ingredients.
If you find that it takes a bit more energy to keep your cool or that you are no longer sleeping through the night I encourage you to look to progesterone as a way to help.   You can go to and take a free hormone quiz to see where you might lie and what you can do with nutrition, supplements and lifestyle changes to feel even better.
Ever since my cycle started again 10 months after having my baby I’ve had 3-5 days of spotting before each period, depression that fluctuates during the month (day 1-2 of cycle I’m happy as a lark, day 3, my dark cloud of depression sets in again…ups and downs from there), hair loss, dry skin, weight gain, headaches,  and I can’t think straight 99% of the time. Oh, and I don’t have to worry about birth control cause I don’t seem to get pregnant easily.
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My point is, if you have severely low progesterone go to a doctor if you can and if you can’t eat healthy as possible and get some progesterone natural cream. You can and more then likely will have a stroke if you let it go too long. I just thought I wasn’t woman enough to handle the changes when I was menstruating and never told anyone, don’t ever just think it’s normal and not ask. I am trying to fix it myself (I have no insurance) but who knows if it will work or not. My period starts tomorrow so we will see.

I’ve been experiencing many of the above symptoms and also an extreme amount of hair loss.  I’m 47 yrs old and I just has a large uterine fibroid removed.  I was hoping that after the removal I’d notice a big positive change.  None so far.  I also have fibrocystic breasts and unexplained lactation.  Do these things also sound like they could fit the picture of low progesterone?  I talked to my obgyn and he suggested I speak to my endocrinologist.  I spoke to my endocrinologist and he told me to talk to my obgyn.  He also said that this was an area of medicine that was “alternative”!  What? Women’s hormone regulation is “alternative”?  Hummm, I’m stumped and don’t know where to go from here.  Thank you and have a great day. 

Progesterone is not made in a smooth fashion. As the picture here shows, progesterone is actually released in pulses. Since most physicians only draw blood from a patient once to check their levels, and use a level of 10 ng/mL to mark the cutoff between “good” and “bad” levels, it is easy to see how the doctor and the patient can be misled into thinking that her levels are too high or too low.
As you can tell, progesterone is a very important hormone and it is a key treatment point in many women’s hormone-related health conditions. If you suspect that low progesterone or estrogen dominance with relative low-progesterone may be affecting your health, the first step is testing your hormones to confirm. From there we have many options, ranging from nutrition changes, to improving digestive health, and then with herbal medicine or bioidentical hormones. This is an area of hormone treatment where we can see profound improvements in your overall health, mood and well being.
The Women Living Naturally website suggests that xenohormones may contribute to estrogen dominance and low progesterone. Xenohormones are man-made synthetic substances that have hormone-like effects. The Natural Hormones website suggests that exposure to synthetic substances, like plastics, may increase estrogen levels and stimulate a lower progesterone levels. Plastics contain xenohormones, which mimic estrogenic activity and create hormone imbalance. Pesticides, herbicides and fungicides that derive from petrochemicals may also contain xenohormones. Solvents and adhesives like fingernail polish and cleaning supplies may contain xenohormones, as well as automobile exhaust and PCBs.

Hi Karoline, thank you for sharing your story. Your hormone panel being menopausal won’t be a surprise, low estrogen, low progesterone and testosterone, so you may want to get your thyroid panel done just to check on things. One of things that happens when we get low estrogen is weight gain. No matter what women do the weight just stays in an effort to keep estrogen stored. There are bio identical hormones available that don’t have the same health issues the synthetic one cause and are good support for this time. I don’t think it would hurt to have a thyroid panel done to ease your mind but we just have to support our bodies with herbs and progesterone cream in an effort to balance to things out. Be sure to have testosterone tested too.