Hi.  Is nausea and headache associated with this?  I am having a hard time convincing my doctors to test my hormone levels.  My Mom, and her Mom, and my great grandma on my mom’s side all had early menopause.  I have been experiencing most of these symptoms,  including hot-flashes.   Because I have been making notes on my weird symptoms,  I have noticed that I know what time of day to expect my hot flashes.  I also noticed that I have been craving the foods that are reccomended to alleviate these symptoms.   I also have a tooth that is withering away, & Yes, I have a dental appointment for that.    I alsohad a re ent eyesight change, and went to the eye doctor,eyes are healthy, just natural aging eyesight.  I am in my very late 30’s. I have been taking a birth control pill for a number of years.  My GYN told me it would be useless to test for menopause because of the birthcontrol.  I also take a prescription for anxiety,  and a doctor recently had to increase the dosage  to help with my increase in symptoms.  At first he wanted yo prescribe me haldol formood swing……. i resonately    refused!!!  I told him I am not aggressive,  or violent in any way, and that Haldol was not appropriate for hormonal mood swings.  Please, I would love to hear a reply on your thoughts on this.        Please, provide more education on the weirder symptoms of early menopause.   
Stopping progesterone abruptly without proper titration can also be problematic. Many have experienced a huge wave and additional surging of progesterone as it comes out of our tissues soon after abrupt withdrawal. It is a very unpleasant experience. An aldosterone surge can occur that leads to electrolyte imbalances ? which in severe cases requires hospitalization.
This isn’t an easy answer.  Stress reduction takes real work.  We cannot just promise to sleep more or to spend more time with ourselves or our families, and then let these promises drift away as life marches on.  Instead, we have to make concrete changes to our schedules, to our jobs, to our relationships, to our feelings about our existence. Often, psychologists can be uniquely helpful, as can group involvement, friendship, spiritual communities, and yoga and meditation.
I have stage 4 endometriosis diagnosed via laparoscopy.We have been ttc for 17 months and then took a break as my docter have put me on Visanne(dienogest).I started bleeding on 20 march and got a positive HCG test on 1 April and the next three days negative HCG test? My docter says the bleeding is from my body that is still “settling” from the Visanne. We have tried Vitex, OPK, BBT, Charting and everything to conceive with no luck.I have endometriosis on my ovary and pelvic wall lines.I don’t know if I ovulate.My doctor said my tubes are fine after my lap but never tested if they are blocked or not. 6 months after excision surgery i had an endometrioma back again.Any ideas on to conceiving?
As you can tell, progesterone is a very important hormone and it is a key treatment point in many women’s hormone-related health conditions. If you suspect that low progesterone or estrogen dominance with relative low-progesterone may be affecting your health, the first step is testing your hormones to confirm. From there we have many options, ranging from nutrition changes, to improving digestive health, and then with herbal medicine or bioidentical hormones. This is an area of hormone treatment where we can see profound improvements in your overall health, mood and well being.
@Barbara, You’re right, taking a bio-identical hormone may negatively affect fertility when they are not needed. Progesterone can increase the chance of keeping a pregnancy in a woman who is chronically low. (to low progesterone and miscarriage is likely) And using some short term supplementation with progesterone can help a woman who is estrogen dominant.

Wow there sure is some confusion out there. I had a complete thyroidectomy at 45 years old after nodules were found after my last pregnancy at 43 years. Since then I have lost over half my hair and my joints ache so bad I crawl around on my hands and knees for the first hour after I get out of bed. The doctor looks at me like I am insane and prescribes antidepressants or narcotics!! I want neither. I think its low progesterone as I am bloated, suffer insomnia due to the excruciating joint pain, irregular periods, dry skin, can’t concentrate or retain anything.. and my FSH comes back that my hormone levels show no sign of menopause. I don’t get it.. but I need the pain to stop and the energy level to deal with a seven year old! Help
Most commonly, a patient will be given a ten-day course of progesterone. When she stops taking the supplement, the lack of progesterone triggers a “reboot” in her system and her normal period will begin. In certain situations—women with a history of depression, diabetes, or abnormal cholesterol—a lower dose or a shorter time frame may be prescribed. Dr. Hjort calls this treatment “a kind of trickery to keep the uterus calm and the cycle short and regular.” It’s possible to see “a 20 to 30 percent reduction in length of flow, heaviness of flow, and massive improvement of regularity in women who have irregular cycles,” she says.

Dr. Hotze: Remember, progesterone is important to help prevent infertility and help maintain good pregnancies, and to help resolve PMS, which is caused by low progesterone…to help prevent cancer, to strengthen thyroid function, to strengthen bone health, help you with your sleep, help you with fluid retention and weight gain…to help you heal brains particularly if you had an injury. It can be used for that. It’s very important for moods, anxiety, and depression. It can help relieve that because it calms you. Finally, if you’ve got migraines and headaches, it can be a Godsend. So, that’s one of the key ingredients.
One of the first steps in protecting the health of our breasts and preventing breast cancer, is to recognize its hormonal risk factors and begin to reduce them. According to the experts, almost all risk factors associated with breast cancer are directly or indirectly linked to an excess of estrogen, or estrogen that is not sufficiently balanced with progesterone, as is the body’s accustomed way. Also known as estrogen dominance, the condition was defined by John R. Lee, M.D., as an imbalance between estrogen and progesterone in which estrogen levels can become too high relative to inadequate progesterone levels. Dr. Lee also emphasized that estrogen can become dominant whether levels are within normal range, high, or even low, if progesterone levels are even lower, relatively speaking. This is a common condition during perimenopause when hormone levels are fluctuating, and at menopause when ovarian hormone production ceases altogether. A growing number of experts believe that correcting this fundamental imbalance is at the heart of preventing and treating breast cancer.
The body is an amazing miracle in action. Every second, millions of reactions are taking place to maintain a perfect balance. People spend years of their lives studying how the body functions and they still don’t know everything there is to know about human life. One aspect of humanity is reproduction. For some women, becoming pregnant seems as easy as simply thinking about a baby. For others, becoming pregnant and maintaining a pregnancy is a very frustrating experience. The hormone progesterone is responsible for several reactions that must take place for a healthy pregnancy to occur. If progesterone is not present in the body at a proper amount, a woman is most likely going to be dealing with infertility and pregnancy loss.
If you track your cycles and find that you ovulate on day 19 for instance, then taking your progesterone levels on day 21 will show that you have low progesterone, but your progesterone might not even be low. 7 days after ovulation in this case brings us to day 26. A blood draw on day 26 would give you an accurate measure of your progesterone levels in this example. After confirming that you ovulated on day 19, you’d have to be tested on day 26 in order to get an accurate reading of your progesterone levels.
I had no idea that cortisol production was involved here. I suffered from low progesterone (without estrogen dominance)about one year ago (at 27 yo). I have since recovered. I have psoriasis, which flares up with increased cortisol production. My psoriasis was at its worst when I had the low p problem. I wonder whether my flare up was a cause or part of a symptom of my problem? If my body was producing more cortisol to sustain the psoriasis, then I would have been loosing out on production of other hormones. My diet was unsuitably low in calories at the time.

Making healthy lifestyle changes can be an alternative to women who can not take hormone replacement therapy or who choose not to do so. Eating a diet rich in fruits and vegetables along with low fat meat and dairy choices can help with the symptoms caused from low progesterone levels. Along with eating healthy a woman should consider taking supplements especially with adequate amounts of calcium, Vitamin D, Vitamin A, and omega 3 fatty acids. Regular exercise can help to promote healthy hormone levels. Most doctors recommend at least 30 minutes of exercise every day. Before starting an exercise program a woman should consult with a physician especially if there are other health concerns that should be considered beforehand such as lung or heart problems.


Please note that content on this website is intended for informational purposes only, and is not intended as a substitute for the advice provided by your physician or other healthcare professional, not is it meant to diagnose or treat a health problem, symptom or disease. Always speak with your physician or other healthcare professional before taking any medication or nutritional supplement, or using any treatment for a health problem. If you have or suspect that you have a medical problem, contact your health care provider promptly. Do not disregard professional medical advice or delay in seeking professional advice because of something you have read on this website. Information provided on this website DOES NOT create a doctor-patient relationship between you and any doctor affiliated with our website.
Glucophage and clomid. About a year and a half later I had my daughter and 4 years later without using any birth control in those years we now have a son! I have ALL the above symptoms! I’ve seen my dermatologist about my face breaking out with no luck. Somedays I wonder how my husband stands me, every time I talk to my OB she wants to put me on birth control pills and I refuse and she gives no other options. I’m in desperate need of advice! 

I have been having pregnancy complications (again) and just read information regarding a possible link to progesterone deficiency. I called my provider to find out what my progesterone levels were, and learned they had never been tested! I had even been seeing a specialist for these problems, which five minutes of internet research showed me are common with progesterone deficiency! I left a message immediately requesting my levels be tested.

Testosterone -­ An important sex hormone for both women and men, although women have much lower levels. Is produced by the ovaries and adrenal glands (right on top of the kidneys), and has a surge at time of ovulation and slight rise just before the menses. Testosterone helps women maintain muscle mass and bone strength, enhances sex drive and helps with overall sense of well-being and zest for life.
Progesterone is not made in a smooth fashion. As the picture here shows, progesterone is actually released in pulses. Since most physicians only draw blood from a patient once to check their levels, and use a level of 10 ng/mL to mark the cutoff between “good” and “bad” levels, it is easy to see how the doctor and the patient can be misled into thinking that her levels are too high or too low.
Yes almost identical happened to me. I think having extremely nosy neighbors for over a year also added to messing up my cycle. I still continued to train with extremely heavy weights and did my cardio also a minimum of 4 times a week. I still have symptoms but I believe things are slowly returning back to normal. I hope your matter is resolved now.
@Marika, Most women I have talked with, when using the cream past their normal luteal phase, if they have ovulated and are not pregnant, it won’t delay menses more than a couple of days. Because once you’ve ovulated it can’t hold off menses for to long. So just go out at least 14 days from ovulation – if you’re tracking basal body temps you should be able to see when you ovulated.
Women commonly take progesterone to help restart menstrual periods that unexpectedly stopped, treat abnormal uterine bleeding associated with hormonal imbalance, and treat severe symptoms of premenstrual syndrome (PMS). Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
Hi! I have low progesterone, as well as very low estradiol and testosterone levels. I just turned 43 and for two years, my hormonal decline has taken my life away. I have no energy whatsoever: Crashing fatigue. I do have hashimotos, but it’s pretty much under control (I’m well versed there). I have known that my progesterone has been dropping for the last 9 years but have had trouble tolerating progesterone. Within two weeks my face turns into a cystic mess and I feel rage. Now that my estradiol is low, I have to find a way to take progesterone in order to supplement with an estradiol/estriol combo. What on earth would cause me to be intolerable to progesterone? I have been trying to take an OTC progesterone oil sublingually. So far, I still break out some, but my feeling is that I’m just not on enough and I fear increasing the dose. I mean, who wants wrinkles and zits at 43 lol? Is it just possible that I’m not taking a high enough dose to stop this madness that I have battled for 9 years? Something’s got to give because my business has come to a stand still and my children no longer have a mother who has the energy to do anything. And sleep? What’s that? Between the insomnia and hot flashes I’m about to lose my mind. Thank you kindly for any advice you can share with me. P.s. I have seen several so-called bioidentical docs and they just seem stumped by me :(.

Although it has been suggested that saliva hormonal testing is perhaps better than blood hormonal testing, it would be wise to work with your doctor so they can explain your results and offer you guidance on further courses of action. This is true even if they choose to administer a blood hormonal test. They will also carry out other hormonal tests which can help you to ascertain vital information about your personal hormonal profile.
Yes, I do use vitex and depending on your levels and how old you are there are a few ways to use it. If you are perimenpausal or menopausal you can use 1 full dropperful of tincture 2 times a day. If you are younger and cycling regularly and have estrogen dominance issues take 1 dropperful 2 times a day from ovulation through day 28. Then get you cycle and do not start again until ovulation. You can use capsules in place of tincture but I like the tincture because you can adjust dosages more easily to find that perfect dose. Hope this helps.

I have been on progesterone cream for a little over year – I am also on supplements for adrenal fatigue from emotional stress and I had irregular, very long cycles, and sometimes no period at all – just spotting when I was supposed to have a period. I also experienced lots of hair loss, fatigue, and pms that lasted for 2 weeks. Progesterone cream has helped my cycle become more regular, my pms greatly improve, and the hair loss stopped. But the one thing left is the weight loss. My cycle is just now becoming 28 to 30 days and I still have some pms so does that mean my hormones still have some balancing left to do?

When a patient complains of fatigue or menopausal discomfort to a doctor, the typical medical workup consists of investigating thyroid function, anemia, and metabolic issues. Female and male hormones are often investigated by way of saliva or serum laboratory tests. Functional or alternative medicine practitioners commonly obtain diurnal cortisol, estrogen, progesterone, DHEA, and testosterone as baseline hormonal information through laboratory studies. While most laboratory studies are normal, DHEA and progesterone level are often low.
I just received test results back that have my progesterone at 47 (vs. 75-270 healthy) and my PG(?) ratio (progesterone to estrogen) at 28 (vs. 100-500 healthy). Clearly, there’s a problem. I got tested b/c my hair has fallen out like you cannot imagine. Scary. Almost bald. I want to use a natural progesterone cream ASAP to try to get the hair growth back but I had a transient ischemic attack (TIA) in 2007. Does that mean I really shouldn’t try a cream? Thank you so much for your GREAT site!

There are a variety of hormonal abnormalities that can lead to infertility. Examples are hypothyroidism (low thyroid function), hyperprolactinemia (high male hormone levels) and luteal phase defect (low progesterone levels). Our physicians are experts in treating these and other endocrinological abnormalities. The IHR experts work closely with couples undergoing the many different types of assisted fertility treatments available. We are renowned for our specialized knowledge and high infertility success rates even in difficult cases. IHR's expertise in hormonal infertility lies in our willingness and ability to individualize our approach to best suit each and every one of our patients. If you have any questions as you review the material on hormonal infertility, please contact us for a FREE Hormonal Infertility E-Mail Consultation.


Stress causes the progesterone level in your body to drop sharply, so symptoms can come back. When you start supplementing, it is a good idea to meditate, let go of your negative reactions to people and circumstances around you, and try to avoid stressful situations. If you are stressed, increase the amount of cream until you are over the stressful time, then slowly reduce back down again.

Disclaimer: Although this web site is not intended to be prescriptive, it is intended, and hoped, that it will induce in you a sufficient level of scepticism about some health care practices to impel you to seek out medical advice that is not captive to purely commercial interests, or blinded by academic and institutional hubris. You are encouraged to refer any health problem to a health care practitioner and, in reference to any information contained in this web site, preferably one with specific knowledge of progesterone therapy.
I am 4 weeks pregnant and was wondering if it is harmful to take Prometrium 400 mg/a day as extra insurance against a miscarriage? I haven’t had my progestrone levels tested, and my RE doesn’t think I need to be tested. For my last pregnancy, I took the same amount, but it was prescribed to me because I had an IUI. This time I got pregnant naturally. Thanks in advance for your advice!
But because estrogen helps eggs to mature, my thinking is that women who have to much (and still adequate amounts of progesterone) may ovulate within weeks/months after birth – much earlier than in the past. So I think that at least 12-18 months of lactation amenorrhea is very probable, sometimes extending beyond that. And “normal” hormones during breastfeeding should include enough prolactin to supress the progesterone production so that the body does not conceive while another baby is still relying on the mother for all of it’s nourishment.

Hi, I’ve just been diagnosed with low progesterone after having the majority of these symptoms. At first I blamed it on coming off the pill last October but as time has gone on and no signs of pregnancy I knew something wasn’t right. I now have been referred on to the fertility clinic to see if I can balance it out! Feel relieved after reading this artical that I’m not the only one! Thanks 
I had a hormonal imbalance before I went on the depo shot since I hit puberty. Not diagnosed by a doctor but it was just very obvious. I went on the depo for 4 years and now I have been off for 7 months and my hormones coming back and I feel like a crazy person.. we’re wanting to get pregnant again so I don’t want to get on the depo again but I don’t want to feel like this anymore. Is there a solution? I know the depo affects progesterone in some way and I wasn’t sure if you could help but I had to ask!
According to the Natural Hormones website, high stress levels may cause lower progesterone, and vice versa. A Christian Broadcasting Network article suggests that stress reduces progesterone, interfering with a woman’s reproductive capacity, and is a leading cause of infertility and miscarriages. A woman’s body requires progesterone to conceive--progesterone prepares the uterine lining for the fertilized egg. Progesterone is also responsible for feeding and nourishing the uterus throughout pregnancy. Stress triggers a woman’s body to produce additional cortisol and adrenaline, effectively diminishing progesterone levels.

Premature labor. Most research suggests that applying progesterone gel into the vagina, alone or along with therapy to delay labor (tocolytic therapy), reduces the risk of premature delivery in some women at high risk of premature birth. However, other research suggests that intravaginal progesterone gel does not decrease the frequency of premature birth in women with a history of premature birth.

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In my opinion having 2 M/C's does not mean that you are having issues. M/C are generally the bodies way of dealing with an issue. I had several misscarriages and they were not caused by fertility issues. As it turned out my husband and I were incompatible and after several tries we finally had our son. Talk to your Dr before making assumptions that the m/c's were nothing more than your body making the correct choice for it.

Progesterone is one of the major female hormones, along with estrogen, produced by the ovaries. These two hormones work together to regulate a woman’s menstrual cycle. Natural progesterone has an identical chemical structure to that made in a woman’s body by the ovarian corpus luteum. It is not the same as the synthetically derived progesterone referred to as progestins, which are chemically modified and recommended by conventional doctors. Progestins have the opposite effect to natural progesterone. They are used as morning after pills to trigger abortions and in birth control pills. To be clear, this discussion deals only with natural progesterone.


6. Ensure adequate magnesium intake. This mineral helps to boost progesterone production by simply keeping you calmer as well as by assisting in the breakdown of estrogen. In times of stress I have used a magnesium oil (which I bought on Amazon) as well as a magnesium supplement. You can also find magnesium in beans, lentils, leafy greens, and  pumpkin seeds.

Autoimmune Hashimoto’s Thyroiditis is the leading cause of hypothyroidism. The gut, as we discussed in the Poor Nutrition section and will discuss again in the closing section, is a key area of focus in healing Hashimoto’s.  When peptides (parts of the protein in foods) cross the gut barrier into the blood stream it stresses the system and the immune system responds by going after those peptides that shouldn’t be there.  But the trouble is that this dysregulated immune system will also attack the body’s own tissue, in this case the thyroid gland.
@Lil, It’s probably best to get copies of your lab tests that have been done so that you can look at them yourself and research what functional ranges should be. And if the spotting is due to low progesterone, you could always try a bio-identical progesterone cream. There are bio-identical pills, but many women (me included) don’t have as good of luck using them.
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Stopping progesterone abruptly without proper titration can also be problematic. Many have experienced a huge wave and additional surging of progesterone as it comes out of our tissues soon after abrupt withdrawal. It is a very unpleasant experience. An aldosterone surge can occur that leads to electrolyte imbalances ? which in severe cases requires hospitalization.

What we know is that it can take anywhere from 4-12 months to bring progesterone levels back up in women with very low progesterone levels. In general we suggest its use, while following a holistic natural fertility program, for a minimum of three months, up to 6 months while paying attention to how the body is responding/shifting before making a change to said program. It would also be a good idea to have progesterone levels monitored during this time to know how levels are shifting and if you might need to adjust the dose, or if you can wean off of progesterone cream. Each woman will be different, so the length of safe use for you will likely be different from the length of safe use for me or another.
The correct levels of progesterone must also be in the right balance with estrogen to regulate your menstrual cycle. Abnormally high levels of progesterone can be caused by abnormalities in your menstrual cycle, dysfunction with your adrenal glands, or being under too much stress. Some of the warning signs that your progesterone levels are constantly too high are fatigue, difficulty losing weight, and decreased sex drive.
Hi there. My periods stopped 2 years ago. I’m 55, so post menopause. My mom had a stroke so i doubt my Doctor would consider giving me HRT. I look and feel hypothyroid (i’m told hypothyroidism and low progesterone after the menopause can go hand in hand). I’m doing everything right ‘diet wise’ and ‘supplement wise’ to give progesterone a helping hand. Also using Serenity progesterone cream am and pm. That’s stopped the flush’s and the feelings like i’m having a heart attack in the night. But my weight just won’t shift and i ‘still’ look like a hypothyroid person. Do you think i should go to the Doctor asking for a thyroid test or a hormone level test? I mean what comes first, sorting out your thyroid or sorting out your hormones? Thanks, Karoline
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