I have been suffering from acne right after certain food, fatigue, headaches, all kinds of allergies, slow metabolism, weight gain, pain(fibromyalgia) for years. All my tests were coming negative. One of the doctor told me that either we are all missing something or you have psycho somatic disorder. I had too much bleeding during periods, recently I went to another gynec and she checked my hormonal level. Very high estrogen and very low progesterone level.
It’s also important to use natural family planning methods like charting so that you can see if you’re actually ovulating. Many women find that using progesterone before ovulation actually suppresses ovulation and they then have an annovulatory cycle. So let’s say that a woman naturally ovulates on day 14, if she began progesterone on day 12, that may cause her not to ovulate. And of course, not all women experience this, but enough so that it’s commonly talked about (personally and in online forums) to wait until after ovulation to begin progesterone. So that might be something to look in to.

Miscarriage. Most research suggests that applying progesterone into the vagina does not reduce the risk of having a miscarriage during the first trimester in women at high risk for miscarriage. Also, injecting progesterone and another steroid hormone into the muscle after undergoing a test used to diagnose birth defects (called an amniocentesis) does not seem to reduce the risk of miscarriage or preterm delivery.
Hello, I have never had a good libido and i am not interested in having sex. It is always painful so i never have looked for having it. I have been married twice and I just put up with it but for the last 5 years I have refused to do anything since it is so painful. Nothing relaxes me. I am now in my 50’s and would like to do something about it. What could it be? otherwise I am healthy and well proportioned.
The cream is often not enough to substantially increase progesterone levels and a bioidentical pill or suppository is usually looked at then. The creams usually have applications that give you 10-30 mgs of progesterone, though it’s hard to tell how much is being absorbed. The pills/suppositories can range up to a couple hundred mgs, though I’d make sure to work on finding out the cause of the low progesterone as being on them long-term isn’t ideal. And some women do have side effects with the supplementation so it’s important to work with your doctor and take just what you need.
Hey I’m 25 I’ve had cysts on my ovaries and have some pretty bad problems with them since I was 15 and have been battling with drs. Since. I finally have caught one drs attention.  I can’t have sex cause it hurts very bad some times I turn wrong it will hurt. But the last time I went to the Dr he told me I have to much progesterone and he wanted to try the pill. But it seems like from reading your article I have way more symptoms of it being to low Rather than having to much.  I have no children. And it makes more since why I haven’t been able to have one. I have terrible periods. Sometimes can’t even walk cause I’m in so much pain. And I bleed a lot more blood than most girls I’ve talked to anyway. And according to my period calendar ovulation happends 4 days after my period idk how accurate that is but it’s accurate about my periods for the most part. Idk I’m just tired of dealing with this and being as tho our drs are known for not doing there job well I was wanting someone else’s opinion. 

My husband and i live in australia, i am 31 & he is 33 and we are both a healthy BMI and we have a 3 year old daughter that was conceived naturally and had a natural birth. We have since been TTC for 2 years with only a “successful pregnancy” ending in early miscarriage at around 6-7 weeks. my cycle has slowly increased from around 23/24 days to now a 26/27 day cycle. i have completed a day 21 progesterone test twice, the results were 17 & 24 which i wonder if that is high enough to sustain a pregnancy, my day 2 FSH was 7.2 & my E2 was 138. this month my HyCoSy came back showing a healthy uterus, clear tubes & good ovaries with 6 eggs maturing in one ovary & 8 eggs maturing in the other at cycle day 8 and my AMH was 9, my husband semen analysis was good, so to date it seems to be unexplained fertility but from my zig zag looking bbt charting it looks like something is out! for quite some time i have been feeling extremely light headed like i could pass out, and foggy in the back of my head and finding it hard to concentrate, fatigued, low libido, recently started having allergies to flowers when i never have in my life, also having night sweats and being far more emotional than i usually am yet every time i see a doctor about this they do blood tests and give no answers and say if nothing comes up they can only assume its panic attacks.. but i had been wondering if its by hormones causing me all this grief and after reading your article it seems to have possibly shed some light! 
I have all these symptoms but I’ve been to several doctors that have stated all my levels are good. There’s absolutely nothing wrong with my. It feels like I’m pregnant!  I’m still experiencing every symptom! All my hormone levels are normal. I’m not pregnant because tests are negative!  Please explain to me how I can continue to get my progesterone checked. I’ve been to several doctors who all say the say thing. Is there something I’m missing? Thank you

This isn’t an easy answer.  Stress reduction takes real work.  We cannot just promise to sleep more or to spend more time with ourselves or our families, and then let these promises drift away as life marches on.  Instead, we have to make concrete changes to our schedules, to our jobs, to our relationships, to our feelings about our existence. Often, psychologists can be uniquely helpful, as can group involvement, friendship, spiritual communities, and yoga and meditation.


Premature labor. Most research suggests that applying progesterone gel into the vagina, alone or along with therapy to delay labor (tocolytic therapy), reduces the risk of premature delivery in some women at high risk of premature birth. However, other research suggests that intravaginal progesterone gel does not decrease the frequency of premature birth in women with a history of premature birth.


Estrogen dominance occurs whenever a woman produces too much estrogen relative to her progesterone levels. Estrogen dominance can occur during perimenopause or menopause, but is becoming more prevalent among women of childbearing age. Excess body fat, chronic stress, and a diet high in sugar and processed starchy carbs can contribute to blood sugar imbalance and hormone dysregulation. When progesterone is low due to estrogen dominance, you’ll likely experience other symptoms like fluid retention, breast tenderness, and irritability.
Any increase in progesterone immediately is a HORRIBLE experience for me, instant weight gain, terrible in every single way. Been to many excellent doctors and done research for years, Something about my metabolism of it goes terribly wrong, and I’m not the only one who cannot tolerate birth control pills or progesterone supplementation. These opinions to raise progesterone need to be qualified with the words “for some people” it’s not horrible to raise progesterone, but it’s absolute POISON for others.
A woman's ovaries may produce high progesterone levels. This hormone is naturally secreted during the second week of her period in a woman who is in child-bearing age. The substances are called progestogens or progestins. They are also found in birth-control pills, in hormones given during menopause for replacement therapy, or in medications to correct abnormal bleeding problems during menses. These hormones are also used to counteract PMS syndrome, infertility, and pregnancy loss. Many women are aware of the effects of too little or too much estrogen, but have never looked up progesterone side effects.
Hi Karoline, thank you for sharing your story. Your hormone panel being menopausal won’t be a surprise, low estrogen, low progesterone and testosterone, so you may want to get your thyroid panel done just to check on things. One of things that happens when we get low estrogen is weight gain. No matter what women do the weight just stays in an effort to keep estrogen stored. There are bio identical hormones available that don’t have the same health issues the synthetic one cause and are good support for this time. I don’t think it would hurt to have a thyroid panel done to ease your mind but we just have to support our bodies with herbs and progesterone cream in an effort to balance to things out. Be sure to have testosterone tested too.
I have hashimotos and hypothyroid. My cycle is clock work every 26 days, no biggie…. wrong! I bleed for 7-10 days and my iron levels won’t come up!!! I have been reading a lot of magnesium with my thyroid. Any suggestions on test? I was put on a progestrone cream based on my symptoms but I swear it was making me anxious unless it’s these winter months. So I’m going to hold off for now. But I wasn’t tested!?!?!

Because estrogen and progesterone receptor sites are very similar at the cellular level, estrogen receptor sites can ?wake up? when occupied by progesterone molecules, enhancing the action of estrogen for a short period of time. It is easy to draw the conclusion that this is a sign the body is responding well to the progesterone, and sufferers are encouraged to ?brave through? this estrogenic effect, as it is supposed to eventually go away. However, ignoring the underlying dysfunction when alerted by the body is a recipe for disaster.
You can browse Drugs A-Z for a specific prescription or over-the-counter drug or look up drugs based on your specific condition. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen.
A: Progesterone is available in several different forms including pills to be taken by mouth, tablets to be inserted into the vagina, and as an injectable medicine. Progesterone also has many uses for female health and regulation of ovulation and menstruation. The most common side effects of progesterone are bloating, breast tenderness, diarrhea, dizziness, drowsiness, dry mouth, headache, heartburn, acne, increased hair growth, vaginal itching or dryness, irritability, muscle pain, nausea, stomach pain or cramping, and vomiting. In addition, some progesterone products contain peanut oil; these products should not be taken by people who are allergic to peanuts. Progesterone may affect blood sugar levels and should be used cautiously in patients with diabetes. Progesterone may increase the risk of developing blood clots. Patients need to notify their healthcare practitioner if they will be having surgery or be confined to a bed or chair for a long period of time (such as a long plane flight). Progesterone should only be used during pregnancy if directed by a physician. If a patient is pregnant or breastfeeding, they should consult with their doctor or healthcare practitioner to discuss any potential risks to the baby. For more information, please consult with your healthcare provider and visit //www.everydayhealth.com/drugs/progesterone. Michelle McDermott, PharmD

Hi Kylee! I’m so sorry you’ve had to deal with these symptoms and aren’t having much luck with a diagnosis from your family doctor. It might be worth a second opinion if you are keen to get to the root cause of your symptoms and have your progesterone levels re-examined. In some areas, there are nurses who also provide hormone balancing and support. You might want to ask around. Please keep me posted with your progress.

I have a question. I’m forty one and the Dr. Put me on Progestrone to shed the lining every month since I might twice a year. He put me on progestrone since those levels were low and try to force my body. He said if the lining is not shed every two or three months it could make a bed for cancer cells to grow. Still no lining shed. Is this common knowledge?
If you have breast pain, you have unopposed an estrogen dominance issue even if tests show “normal” level of progesterone. I had the same issues with estrogen dominance breast pain. I read about and tried topical iodine therapy along with prometrrium (bio identical progesterone) prescribed by my gyno….this worked great for all my pms and then peri menopause symptoms. Whenever I have a flare up of breast pain, I generously coat the iodine evenly over breasts and it works within hours! I was amazed it actually worked! Studies show your body will only absorb the amount of iodine it needs so no risk of overdosing on it. I buy the individually wrapped iodine pads and keep some with me at all times. Also I have tried over the counter progesterone creams and only had intolerable side effects. Ask your doctor if you can give Prometrium a try. In fact don’t ask TELL your doc you want to try it and if they won’t find a new gyno who is more up to date!
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